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Funding Opportunity for NIH Human Virome Program

  • 30 Oct 2024 11:51 AM
    Message # 13425267

    Please see the notice below:

    Date:    Tue, 29 Oct 2024 14:38:50 +0000
    From:    "Murcia, Ellie (NIH/OD) [E]" <murciae@OD.NIH.GOV>
    Subject: New Notice of Funding Opportunity for NIH Human Virome Program

    The NIH Common Fund issued a notice of funding opportunity<https://commonfund.nih.gov/humanvirome/fundingopportunities> (NOFO) for the Human Virome Program (HVP)<https://commonfund.nih.gov/humanvirome/>. The overall goal of the HVP is to characterize the human virome, including viruses with eukaryotic and prokaryotic hosts. The HVP will also create tools, models, and methods that will enable in-depth study of the virome's breadth and variation, its association with host factors, and its influence on health and disease. The HVP consists of four initiatives that will work synergistically to achieve the goals of the program. These initiatives will be:

      1.  Characterizing the human virome and its dynamics by utilizing longitudinal, demographically diverse (i.e., age, sex, race, ethnicity, etc.) human cohorts.
      2.  Facilitating the discovery and annotation of viruses by developing tools, models, and methods that will improve detection, sensitivity, contaminant removal, and scalability.
      3.  Studying interactions between the virome and the human host, as well as with other components of the human microbiome.
      4.  Creating a Consortium Organization and Data Collaboration Center (CODCC) that will serve as an organizational and cooperation hub for the HVP Consortium and external groups and through the creation of a human virome catalog and data portal.

    The new funding opportunity "Human Virome Program: Developing novel and innovative tools to interrogate and annotate the human virome (U01 Clinical Trial Not Allowed) RFA-RM-24-009<https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-24-009.html>" seeks to address the technological challenges that are currently hindering robust interrogation of the constituents and functionality of the human virome. Despite major advances in sequencing technology and computational analysis of large sequence data sets, challenges remain in examining viruses. This NOFO solicits applications to develop innovative and novel tools, models, and methods to overcome the major challenges in identifying and characterizing viruses, as well as the development of computational and bioinformatics tools to enhance the analysis of the human virome. This NOFO seeks novel applications on new tools, methods and techniques that do not overlap with what is currently funded through RFA-RM-23-018<https://commonfund.nih.gov/humanvirome/fundedresearch>.

    All applicants are strongly encouraged to contact NIH Staff at HumanVirome@od.nih.gov<mailto:HumanVirome@od.nih.gov> to discuss the alignment of their proposed work with the goals of this NOFO and the HVP. A list of frequently asked questions with answers is available on the website<https://commonfund.nih.gov/humanvirome/faq>. Prospective applicants are invited to view the pre-application webinar for RFA-RM-23-018<https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-23-018.html>, which was recorded on October 16, 2023. NIH staff discussed the Human Virome initiative and answered questions about the application and review process. The webinar recording<https://www.youtube.com/watch?v=r0YyV6UgA4Y> and webinar slides<https://commonfund.nih.gov/sites/default/files/HVP-webinar-2023-10-16-508.pdf> are now available.

    More information on the HVP can be found at https://commonfund.nih.gov/humanvirome.
    Subscribe to the listserv<https://list.nih.gov/cgi-bin/wa.exe?SUBED1=HUMANVIROME&A=1> to receive updates from the Human Virome program.


    The NIH Common Fund<https://commonfund.nih.gov/> supports high-impact programs designed to foster collaboration across NIH Institutes, Centers, and Offices. As the nation's primary medical research agency, the NIH conducts and supports research that leads to medical breakthroughs, advancing public health.


    The National Institutes of Health (NIH) - "The Nation's Medical Research Agency" - includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical, and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about the NIH and its programs, visit the NIH website.


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